We are developing membrane protein nanoparticles

We just received the Feasibility Fund grant to develop membrane protein nanoparticles based baculoviruses. The aim is to develop technology to improve and simplify the production and use of membrane proteins in biomedical studies, as this is one of the limiting steps in drug development. We produce membrane proteins is Sf9 insect cells, which can also be used to express membrane proteins on baculovirus nanoparticles. These stable particles can then be used in various bioassays to test if drugs are interacting with specific membrane proteins.
You can read more about it in here (in Estonian).

Blue-white test in generation of bacmid, which is then used for transfection of Sf9 cells. Photo by Anni Allikalt.

Protein production in Sf9 insect cells. Photo by Anni Allikalt.